ncRNA name | hsa-miR-29 |
ncRNA Category | miRNA |
Disease name | age-related macular degeneration (AMD) |
Species | Homo sapiens |
Tissues/Cell_line | primary human RPE cells; human RPE cell line ARPE-19; human embryonic kidney cell line HEK293 |
Methods | transfection, luciferase reporter assay, Western blot, qPCR, autophagy flux assay, immunofluorescence |
Expression pattern | down-regulated |
Functional description | miR-29 enhances autophagy which aids in removal of protein aggregates. |
PubMed ID | 30513336 |
Year | 2019 |
Title | MicroRNA-29 enhances autophagy and cleanses exogenous mutant αB-crystallin in retinal pigment epithelial cells. |
Drug-related ncRNA | NO |
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